Diclofenac topical Pregnancy Warnings. In animal studies, no evidence of teratogenicity was observed in mice, rats, or rabbits given this drug during organogenesis at doses up to approximately 5, 5, and 10 times, respectively, the maximum recommended topical dose despite the presence of maternal and fetal toxicity at these doses.
Mechanism of Action: Voltaren contains diclofenac, a non-steroidal anti-inflammatory drug (NSAID) that works to reduce arthritis- pain by stopping the body from producing a substance that causes pain. 4. Lidocaine, on the other hand, works to reduce pain by blocking nerve signals, which results in a numbing sensation.
Voltaren Gel is a non-steroidal anti-inflammatory drug (NSAID) that is widely used for the treatment of pain and inflammation in humans. It is a topical gel that is applied directly to the skin, and it is absorbed into the body through the skin.VOLTAREN-XR has analgesic, anti-inflammatory, and antipyretic properties. The mechanism of action of VOLTAREN-XR, like that of other NSAIDs, is not completely understood but involves inhibition of cyclooxygenase (COX-1 and COX-2). Diclofenac is a potent inhibitor of prostaglandin synthesis in vitro. Diclofenac concentrations reached during